Adolfo A Ferrando Selected Research

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)

1/2022	Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL.
12/2021	MAPK-ERK is a central pathway in T-cell acute lymphoblastic leukemia that drives steroid resistance.
5/2020	Modeling NOTCH1 driven T-cell Acute Lymphoblastic Leukemia in Mice.
1/2020	Combinatorial ETS1-dependent control of oncogenic NOTCH1 enhancers in T-cell leukemia.
12/2019	GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and Leukemia.
1/2018	The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia.
1/2018	Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia.
1/2018	Leukemia-specific delivery of mutant NOTCH1 targeted therapy.
1/2017	Synergistic antileukemic therapies in NOTCH1-induced T-ALL.
1/2016	A Case of T-cell Acute Lymphoblastic Leukemia Relapsed As Myeloid Acute Leukemia.

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Adolfo A Ferrando Research Topics

Disease

36	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2022 - 07/2003
26	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2022 - 03/2004
24	Leukemia 01/2022 - 10/2002
22	Neoplasms (Cancer) 01/2022 - 12/2003
4	T-Cell Leukemia (Leukemia, T Cell) 11/2010 - 12/2003
3	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 01/2021 - 02/2014
3	Lymphoma (Lymphomas) 01/2021 - 12/2003
2	Glucocorticoid Receptor Deficiency 01/2022 - 12/2013
2	T-Cell Lymphoma (Lymphoma, T Cell) 01/2021 - 06/2015
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2017 - 07/2004
2	Genetic Translocation (Chromosomal Translocation) 10/2011 - 11/2004
2	Carcinogenesis 12/2003 - 02/2003
1	Brain Neoplasms (Brain Tumor) 01/2022
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 12/2021
1	Thrombocytopenia (Thrombopenia) 12/2019
1	Drug-Related Side Effects and Adverse Reactions 12/2019
1	Neuroblastoma 10/2016
1	Sarcoma (Soft Tissue Sarcoma) 10/2016
1	Metaplasia 07/2012

Drug/Important Bio-Agent (IBA)

11	Transcription Factors (Transcription Factor)IBA 11/2021 - 03/2004
5	Phosphotransferases (Kinase)IBA 01/2022 - 12/2013
5	DNA (Deoxyribonucleic Acid)IBA 02/2014 - 12/2003
4	ChromatinIBA 01/2022 - 10/2014
4	Pharmaceutical PreparationsIBA 01/2018 - 02/2003
4	Proteins (Proteins, Gene)FDA Link 10/2014 - 12/2003
4	Gamma Secretase Inhibitors and ModulatorsIBA 06/2013 - 10/2007
3	RNA (Ribonucleic Acid)IBA 02/2014 - 12/2003
3	GlucocorticoidsIBA 12/2013 - 01/2009
2	ruxolitinibIBA 12/2021 - 11/2015
2	Janus Kinase InhibitorsIBA 12/2021 - 03/2015
2	LigandsIBA 05/2020 - 08/2008
2	5'-Nucleotidase (5' Nucleotidase)IBA 01/2020 - 01/2018
2	Protein Tyrosine PhosphatasesIBA 10/2016 - 06/2010
2	CytokinesIBA 03/2015 - 06/2010
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 07/2012 - 01/2012
2	Interleukin-7 (Interleukin 7)IBA 09/2011 - 03/2004
2	Biological ProductsIBA 03/2004 - 10/2003
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2022
1	ErbB Receptors (EGF Receptor)IBA 01/2022
1	CholesterolIBA 01/2022
1	AcidsIBA 01/2022
1	Tyrosine Kinase InhibitorsIBA 01/2022
1	Histone MethyltransferasesIBA 01/2022
1	osimertinibIBA 01/2022
1	Protein Kinase InhibitorsIBA 01/2022
1	Mevalonic Acid (Mevalonate)IBA 01/2022
1	Mechlorethamine (Nitrogen Mustard)FDA Link 12/2021
1	AZD 6244IBA 12/2021
1	SteroidsIBA 12/2021
1	Alkylating AgentsIBA 12/2021
1	Histone Deacetylase InhibitorsIBA 12/2021
1	romidepsin (FK228)FDA Link 12/2021
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2021
1	purineIBA 01/2020
1	navitoclaxIBA 12/2019
1	Antineoplastic Agents (Antineoplastics)IBA 12/2019
1	DT2216IBA 12/2019
1	snake venom protein C activatorIBA 12/2019
1	Nucleosomes (Nucleosome)IBA 12/2019
1	Monomeric GTP-Binding ProteinsIBA 12/2018
1	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 01/2018
1	ThapsigarginIBA 01/2018
1	Sarcoplasmic Reticulum Calcium-Transporting ATPasesIBA 01/2018
1	Heat Shock Transcription FactorsIBA 01/2018
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2018
1	2-mercaptopurineIBA 01/2018
1	proto-oncogene protein Spi-1IBA 12/2017
1	GuanineIBA 01/2017
1	Methotrexate (Mexate)FDA LinkGeneric 10/2016
1	Vincristine (Oncovin)FDA LinkGeneric 10/2016
1	Immunoglobulins (Immunoglobulin)IBA 01/2016
1	Notch1 ReceptorIBA 01/2016
1	Tumor Suppressor Protein p14ARF (p14ARF)IBA 01/2016
1	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2016
1	Janus Kinase 1IBA 11/2015
1	nelarabine (506U78)FDA Link 08/2015
1	PerhexilineIBA 04/2015
1	Carnitine (L-Carnitine)FDA LinkGeneric 04/2015
1	Histones (Histone)IBA 10/2014
1	Polycomb Repressive Complex 2IBA 10/2014
1	Lysine (L-Lysine)FDA Link 10/2014
1	Intergenic DNA (Junk DNA)IBA 10/2014
1	ElementsIBA 10/2014
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 12/2013
1	MK 2206IBA 12/2013
1	Janus KinasesIBA 10/2013
1	nirogacestatIBA 07/2012
1	Dexamethasone (Maxidex)FDA LinkGeneric 07/2012
1	Homeodomain Proteins (Proteins, Homeobox)IBA 11/2010
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 08/2010
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 08/2010
1	alpha chain interleukin-7 receptorIBA 04/2009
1	Glucose (Dextrose)FDA LinkGeneric 04/2008

Therapy/Procedure

24	Therapeutics 12/2021 - 07/2003
3	Combination Drug Therapy (Combination Chemotherapy) 10/2016 - 10/2003
3	Drug Therapy (Chemotherapy) 10/2016 - 12/2004
1	Precision Medicine 01/2018
1	Transplantation 12/2017
1	Induction Chemotherapy 08/2010